Though rare, occasionally the name service on a an F5 3DNS system will lock up and refuse to answer queries. On many production systems, rebooting the system isn't an option; especially when the BIG-IP portion of the system is still happily balancing.
For the most part, F5 BIG-IP and 3DNS are solid appliances, with most management tasks via their web-interface. Sometimes it's quicker to the use a command line interface (CLI), especially when the management task in question isn't available from the web.
The problem is that there isn't a way to restart the name service without rebooting, at least within the web-based administrative panel. You can restart the service if you shell into the system as root:
f5-host:~# /etc/bigstart/scripts/named-ctrl restart
Actually, all of the system startup scripts are in that same directory. Good to know if something ever breaks down.